We are home to many facilities which collaborate across campus to enhance the aim and support for institutional research. Here is a list of research cores which are affiliated with the College of Biological Sciences.
Department of Evolution and Ecology
- The UCDNA Sequencing Facility can sequence double-stranded and single-stranded templates from purified plasmids, BACs, cosmids, and PCR products. This facility's instruments are capable of processing approximately twelve 96-well plates in a 24-hour period.
Department of Molecular and Cellular Biology
- The LM Imaging Facility utilizes advanced fluorescence microscopy resources which specialize in live cell imaging and super-resolution methods.
- The Biological Electron Microscopy Facility encompasses expertise and imaging systems across the spatial resolution scale, from imaging macromolecular assemblies, subcellular organelles and whole-preserved multicellular tissues.
Department of Plant Biology
- The Research Greenhouses include the Core Greenhouse Complex and the Orchard Park Facility, which support 24 total greenhouses.
- The Bioinformatics Core provides expertise and infrastructure for the acquisition, curation, analysis and distribution of large complex biological datasets, with an emphasis on sequence data.
- The DNA Technologies Core provides Illumina high-throughput sequencing, PacBio long read sequencing, as well as Fludigm EP1 and Illumina BeadArray high throughput SNP genotyping. The DNA Technologies Core further offers many sequencing-associated services such as library preparation and QC, as well as consultations on project design.
- The Expression Analysis Core offers many RNA sequencing options such as ribosomal RNA-depletion, polyA enrichment, strand-specific sequencing and ultra-low input libraries.
- The Metabolomics Core provides untargeted and metabolite target analyses for a wide range of biochemical pathways, covering over 1,200 identified metabolites with validated analytical methods and known mass spectra and retention times.
- The Proteomics Core provides state-of-the-art analytical proteomic services with particular emphasis on label-free quantitative proteomic profiling, the analysis of macromolecular complexes, the post-translational modification of their constituents and standard protein identification from complex protein mixtures.
- The TILLING Core provides mutants for rice, Arabidopsis thaliana, and tomato as well as other species on request. TILLING (Targeting Induced Local Lesions IN Genomes) is a reverse genetic technique that uses chemical mutagenesis to create libraries of mutagenized individuals that are subjected to high-throughput sequencing for discovery of mutations.
The Office of Research Core Facilities Program promotes a world-class research infrastructure at UC Davis that enables scientific excellence, technology development and outstanding innovations for researchers on campus and the scientific community.