Cellular and Microbiology

New Cryo-Electron Microscope Powers Biological Sciences Discovery

February 18, 2020
Chancellor Gary S. May and Mark Winey, dean of the College of Biological Sciences, recently cut the ribbon on a new cryo-EM facility in Briggs Hall. The $2.5 million microscope is open to all campus researchers. It can collect thousands of images a day to assemble into movies showing how proteins and other biomolecules do their work.

Mitochondrial Chitter-Chatter: Unveiling the Molecular Structures of Cellular Respiration

September 03, 2019
In order to generate energy, our bodies transfer electrons from food—sugars, fats and proteins—to molecular oxygen, which allows our cells to respire and function. Performed by the mitochondrial electron transport chain (ETC), this process creates ATP, the “molecular currency” for energy in the cell. In a Molecular Cell study, Assistant Professor James Letts, Department of Molecular and Cellular Biology, and colleagues reveal further nuances of the ETC.

The Infection Heist: How Social Viruses Team Up for the Perfect Score

July 11, 2019
Much like characters in a bank heist, viruses in competitive environments can collaborate for their share of the "score" of successfully co-infecting hosts. But these relationships may change once inside the host cell, according to Assistant Professor Samuel Díaz-Muñoz​.

Disease-Causing Nibbling Amoeba Hides by Displaying Proteins From Host Cells

April 30, 2019
A parasitic amoeba that causes severe gut disease in humans protects itself from attack by biting off pieces of host cells and putting their proteins on its own surface, according to a study by microbiologists at the University of California, Davis.