Molecular imaging, cellular imaging, development of diagnostic and therapeutic agents, magnetic resonance imaging, novel contrast agents, multimodal imaging, and imaging agents. Applications to cardiovascular and other disease systems.
Grad Group Affiliations
Specialties / Focus
- Molecular Medicine
- BIM 110 Capstone Senior Design, Fall, Winter,Spring
- BIM 88V Introduction to Research, Winter
- 0 PhD Biological Sciences UCI
- 0 MS Electrical Engineering UCLA
Wang S, Jarrett BJ, Kauzlarich S, Louie AY* Core/Shell Quantum Dots with High Relaxivity and Photoluminescence for Multimodality Imaging, JACS (2007) 129(14) 3848-3856.
Tu T, Louie AY*: Photochromically-Controlled Reversibly-Activatable MRI and Optical Contrast Agent, Chemical Communications (2007) 10.1039/b616991k.
Gustafsson, Youens S, Louie AY*: Development of Contrast Agents Targeted to Macrophage Scavenger Receptors for MRI of Vascular Inflammation, Bioconjugate Chemistry (2006) 17:538-547.
Jarrett BJ, Frendo M, Vogan J, Louie AY*: Size controlled synthesis of dextran sulfate coated iron oxide nanoparticles for magnetic resonance imaging, Nanotechnology (2007) 18(3):035603.
A. Y. Louie, M. HÃber, E. T. Ahrens, U. RothbÃ¤cher, R. Moats, R. Jacobs, S. E. Fraser, T.J. Meade, 2000, "In vivo visualization of gene expression by magnetic resonance imaging," Nature Biotechnology 18: 321-325.
Louie AY, “Multimodal Imaging Probes” (2010) Chemical Reviews 110(5): 3146–3195.
Jarrett BJ, Correa C, Ma KW, Louie AY*, “Multimodal Imaging of Vascular inflammation with targeted MRI/PET contrast agents" PLoS One (2010) 5(10:e13254-.
Tu C, Ng T, Sohi H, Palko H, House A, Jacobs R, Louie AY “Receptor-targeted Iron Oxide Nanoparticles for Molecular MR Imaging of Inflamed Atherosclerotic Plaques” (2011) Biomaterials 32, 7209.
Wong RM, Gilbert D, Liu K, Louie AY* “Rapid Size-Controlled Synthesis of Dextran-Coated, Copper-Doped Iron Oxide Nanoparticles” (2012) ACS Nano 6 (4), pp 3461–3467 DOI: 10.1021/nn300494k.
Kruttwig K, Yankelevich DR, Brueggeman C, Tu C, L’Etoile N, Knoesen A, Louie AY* “Reversible low-light induced photoswitching of crowned spiropyran-DO3A complexed with gadolinium(III) ions” (2012) Molecules 17, 6605-6624;
Balmond E, Tautges B, Faulkner A, Or V., Hodur B, Shaw JT, Louie AY* Comparative Evaluation of Substituent Effect on the Photochromic Properties of Spiropyrans and Spirooxazines”. (2016) Journal of Organic Chemistry, 81(19):8744-8758 DOI 10.1021/acs/6b1193.
Tang T, Valenzuela A, Petit F, Chow S, Leung K, Gorin F, Louie AY*, Dhenain M*, “In vivo MRI of functionalized iron oxide nanoparticles for brain inflammation” (2018) Contrast Media and Imaging, in press.