Clare Yellowley

Clare Yellowley

Position Title

Department of Anatomy, Physiology and Cell Biology, School of Veterinary Medicine

VM3A 2307

Profile Introduction

Bone and cartilage cell biology; Bone regeneration, fracture healing, hypoxia, mechanotransduction

Research Interests

Bone and cartilage cell biology; Skeletal stem cells, Mechanotransduction, hypoxia, cell migration, Orthopaedics, Fracture healing

Grad Group Affiliations

  • Comparative Pathology
  • Molecular, Cellular and Integrative Physiology

Specialties / Focus

  • Cellular Physiology


  • vet 403 Musculoskeletal
  • vet 401 Basic Foundations

Professional Societies

  • American Society for Bone and Mineral Research
  • Orthopaedic Research Society
  • European Calcified Tissue Society
  • Biophysical Society


  • 1995 PhD Physiology Bristol University, UK
  • 1991 BS Anatomy Aberdeen University, UK


Select Publications

Wong A, Loots GG, Yellowley CE, Dosé AC, Genetos DC. (2015) Parathyroid hormone regulation of hypoxia-inducible factor signaling in osteoblastic cells. Bone. Jul 4;81:97-103.

Wilson SS, Wong A, Toupadakis CA, Yellowley CE. (2015) Expression of angiopoietin-like protein 4 at the fracture site: Regulation by hypoxia and osteoblastic differentiation. J Orthop Res. Sep;33(9):1364-73.

Kilgallon CP, Larsen S, Wong A, Yellowley C. (2015) Analysis of a collagen II degradation protein C2C and a collagen II formation protein CP II in serum of Asian elephants (Elephas maximus). J Zoo Wildl Med. 2015 Mar;46(1):146-9.

Soicher MA, Christiansen BA, Stover SM, Leach JK, Yellowley CE, Griffiths LG, Fyhrie DP. (2014) Remineralized bone matrix as a scaffold for bone tissue engineering. J Biomed Mater Res A. Dec;102(12):4480-90.

Wong A, Ghassemi E, Yellowley CE. (2014) Nestin expression in mesenchymal stromal cells: regulation by hypoxia and osteogenesis. BMC Vet Res. Aug 5;10:173

Genetos DC, Wong A, Weber TJ, Karin NJ, Yellowley CE. (2014) Impaired osteoblast differentiation in annexin A2- and -A5-deficient cells. PLoS One. Sep 15;9(9):e107482.

Chung DJ, Wong A, Hayashi K, Yellowley CE. (2014) Effect of hypoxia on generation of neurospheres from adipose tissue-derived canine mesenchymal stromal cells. Vet J. Jan;199(1):123-30.

Bhandal J, Hayashi K, Kim SY, Klein M, Wong A, Toupadakis CA, Muir P, Yellowley CE. (2013) Detection of bacterial DNA by PCR in dogs with stifle pathology. Vet Surg. Oct;42(7):814-8.

Toupadakis CA, Granick JL, Sagy M, Wong A, Ghassemi E, Chung DJ, Borjesson DL, Yellowley CE. (2013) Mobilization of endogenous stem cell populations enhances fracture healing in a murine femoral fracture model. Cytotherapy. 2013 Sep;15(9):1136-47.

Chung DJ, Hayashi K, Toupadakis CA, Wong A, Yellowley CE. (2012) Osteogenic proliferation and differentiation of canine bone marrow and adipose tissue derived mesenchymal stromal cells and the influence of hypoxia.  Res Vet Sci. 2012 Feb;92(1):66-75.

Toupadakis, C.A., Wong, A., Genetos, D.C., Chung, D-J., Murugesh, D. Anderson, M.J., Loots, G.G. Christiansen, B.A., Kapatkin, A.S., Yellowley, C.E. (2012) Long-term administration of AMD3100, an antagonist of SDF-1/CXCR4 signaling, impairs fracture repair. Journal of Orthopaedic Research. Nov;30(11):1853-9.

Yellowley, C.E. (2012) The biology of stem cells and their role in tissue repair. Journal of Equine Veterinary Science. 32(10):661-662.