Craig Benham

Craig Benham

Position Title

Genome Center

2251 Academic Surge

Research Interests

structural transitions in stressed DNA molecules

This research group has developed statistical mechanical methods to computationally analyze the occurrence of structural transitions in stressed DNA molecules.

Grad Group Affiliations

  • Integrative Genetics and Genomics


  • 1972 PhD Mathematics Princeton University
  • 1971 MA Mathematics Princeton University
  • 1968 BA Mathematics Swarthmore College


Hatfield GW and CJ Benham. 2002. DNA topology-mediated control of global gene expression in Escherichia coli. Annual Review of Genetics. :in press

Benham CJ, Savitt A and WR Bauer. 2002. Extrusion of an imperfect palindrome to a cruciform in superhelical DNA: complete determination of energetics based upon a statistical mechanical model. Journal of Molecular Biology. 316:563-580

Mielke C, Christensen M, Westergaard O, Bode J, Benham CJ and M Breindl. 2002. Multiple Collagen I Gene Regulatory Elements Have Sites of Stress-Induced DNA Duplex Destabilization and Nuclear Scaffold/Matrix Association Potential. Journal of Cellular Bioc