Daniel Runcie

Daniel Runcie

Position Title
Assistant Professor

Department of Plant Sciences, College of Agricultural and Environmental Sciences

Robbins 278

Research Interests

Computational and genomic approach to plant developmental biology and evolution

Research in our lab focuses on genetic variation and plasticity. We try to identify molecular pathways underlying phenotypic differences among genotypes, particularly differences in how each genotype reacts to dynamic environments. Our goals are to improve predictions of crop performance, learn about forces that shape the evolutionary histories of natural populations, and identify critical systems that limit plant responses to climate change.

Grad Group Affiliations

  • Biophysics
  • Biostatistics, Statistics
  • Horticulture and Agronomy Graduate Group
  • Molecular, Cellular, and Integrative Physiology
  • Plant Biology

Specialties / Focus

  • Computational and Theoretical Biology
  • Molecular Physiology


  • PLS 205 Experimental Design and Analysis, Winter
  • BIT 150 Bioinformatics, Fall


  • 2012 PhD Biology Duke University
  • 2012 MS Statistics Duke University
  • 2005 BS Biology Williams College


Hine, E., Runcie, D. E., McGuigan, K. & M.W. Blows (2018). Uneven Distribution of Mutational Variance Across the Transcriptome of Drosophila serrata Revealed by High-Dimensional Analysis of Gene Expression. GeneticsLink

Runcie, D. E., N. Dorey, D. A. Garfield, M. Stumpp, S. Dupont & G. A. Wray. (2016) Genomic characterization of the evolutionary potential of the sea urchin Strongylocentrotus droebachiensis facing ocean acidification. Genome Biology and Evolution. Link

Hamilton, JA, Harta, AT, Runcie, D. E., El Kayala, W, Arango-Veleza, A, Cook, JEK. (2016). The joint influence of photoperiod and temperature during growth cessation and development of dormancy in white spruce (Picea glauca). Tree PhysiologyLink

Burghardt, L, Runcie, D. E., Wilczek, A, Cooper, M, Roe, J, Welch, SM, Schmitt, J. (2015). Fluctuating warm temperatures decrease the effect of a key floral repressor on flowering time in Arabidopsis thalianaNew PhytologistLink

Donohue, K., Burghardt, L. T., Runcie, D. E., Bradford, K. J., & Schmitt, J. (2014). Applying developmental threshold models to evolutionary ecology. Trends in Ecology & Evolution. doi:10.1016/j.tree.2014.11.008. Link

Garfield, D. A, Runcie, D. E, Babbitt, C. C., Haygood, R., Nielsen, W. J. and G. A. Wray. (2013). Evolvability and Robustness in a Developmental Gene Regulatory Network. PloS Biology. 11(10) e1001696EP–. Link

Runcie, D. E., and Mukherjee, S. (2013). Dissecting High-Dimensional Phenotypes with Bayesian Sparse Factor Analysis of Genetic Covariance Matrices. Genetics, 194, 753-767. Link

Runcie D. E., Wiedmann, R., Archie, E. A., Altmann, J., Wray, G. A., Alberts, S. C., and J. Tung. (2013). Social environment influences the relationship between genotype and gene expression in wild baboons. Philos T Roy Soc B, 368, 20120345-20120345. Link

Runcie, D. E., Garfield, D. A. Wygoda, J. A., Mukherjee, S. and G. A. Wray. (2012). Genetics of gene expression responses to temperature stress in a sea urchin gene network. Mol Ecol, 21, 4547-4562. Link

Runcie, D. E. and M. A. F. Noor. (2009). Sequence signatures of a recent chromosomal rearrangement in Drosophila mojavensis. Genetica. 136 (1) pp. 5-11. Link