Fern Tablin

Position Title
Professor of Anatomy, Physiology, and Cell Biology

Unit
Department of Anatomy, Physiology and Cell Biology, School of Veterinary Medicine

4329 Vet Med 3A
Bio

Profile Introduction

The Tablin Laboratory is interested in all things platelets. The major focus of the laboratory is how exposure to air pollution can result in platelet up-regulation leading to activation, thrombosis and even stroke. We use biochemical, cell biology and molecular biological techniques to answer these questions.

Research Interests

Platelet physiology, platelet signaling

Grad Group Affiliations

  • Comparative Pathology

Specialties / Focus

  • Cell Biology
  • Cellular Responses to Toxins and Stress

Labs

  • Investigative Hematology Laboratory
    • Ronald Li, graduate student
    • Monica Pombo, graduate student
    • Danh Hyunh, junior specialist

Honors and Awards

  • Fellow, American Association for the Advancement of Science, elected 2003

    Professional Societies

    • American Society for Cell Biology
    • International Society of Thrombosis and Haemostasis
    • AAAS
    • North American Society for Thrombosis and Hemostasis

    Degrees

    • 1973 BA History University of Pennsylvania
    • 1980 VMD Veterinary Medicine University of Pennsylvania
    • 1984 PhD Anatomy University of Pennsylvania

    Publications

    Tablin,F., Schumacher, T., Pombo, M., Marion, C.T., Huang, K., Norris, J.W., Jandrey, K.E., and M.D. Kittleson.  Platelet activation in cats with hypertrophic cardiomyopathy. J. Vet. Intern. Med. 28:411-8, 2014

    Textor, J.A., Murphy K.C., Leach, J.K. and F. Tablin.  Ultrastructure and growth factor content of equine platelet-rich fibrin gels.  Am. J. Vet. Res. 75:392-401, 2014

    Tablin, F., den Hartigh, L.J., Aung, H.H., Lame, M.W., Kleeman, M.J., Ham, W., Norris, J.W., Pombo, M. and D.W. Wilson.  Seasonal influences on CAPs exposures: differential responses in platelet activation, serum cytokines and xenobiotic gene expression.  Inhal. Toxicol. 24:506-517, 2012

    denHartigh, L.J., Lame,M.W., Ham, W., Kleeman, M.J., Tablin, F. and D.W. Wilson. Endotoxin and polycyclic aromatic hydrocarbons in ambient fine particular matter from Fresno California initiate human monocyte inflammatory responses mediated by reactive oxygen species.  Toxicol In Vitro 24:1993-2002, 2010.

    Wilson, D.W., Aung, H.H., Lame, M.W., Plummer, L., Pinkerton, K.E., Ham, W., Kleeman, M., Norris, J.W. and     F.Tablin. Exposure of mice to concentrated ambient particulate matter results in platelet and systemic            cytokine activation.  Inhal. Toxicol. 22:267-276, 2010. 

    Gousset, K., Tsvetkova, N.M., Crowe, J.H. and F. Tablin. Important role of raft aggregation in the signaling events of cold-induced platelet activation. Biochimica et Biophysica Acta 1660:7-15, 2004.

    Gousset, K., Wolkers, W.F., Tsvetkova, N.M., Oliver, A.E., Field, C.L., Walker, N.J., Crowe, J.H. and F. Tablin. Evidence for a physiological role for membrane rafts in human platelets. Journal of Cellular Physiology 190:117-128, 2002

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