Research Interests

plant microbe interactions

Research in my laboratory includes studies on the mechanisms controlling pathogen evolution and virulence as well as plant resistance signaling cascades. A common thread to the research that is conducted in the laboratory is the use of the Gram-negative bacterium, Pseudomonas syringae, for understanding how disease is caused on susceptible genotypes whereas defense signaling is elicited on resistant plant genotypes.

Grad Group Affiliations

• Plant Biology

Specialties / Focus

• Molecular Biology, Biochemistry and Genomics

Labs

• 565 and 575 Hutchison Hall http://www.coakerlab.org
  • James Mitch Elmore, Graduate Student Daniel Lin, Graduate Student Elizabeth Henry, Graduate Student DongHyuk Lee, Graduate Student Jose Rufian, Visiting Graduate Student YiHsuan Chiang, Postdoctoral scholar Koste Yadeta, Postdoctoral scholar Shree Thapa, Postdoctoral scholar

Honors and Awards

• Faculty 1000 of Biology Must Read Plant Biology Paper, 2005
• William H. Krauss Director's Award for Research Excellence, The Ohio State University, 2004
• Phi Kappa Phi Honors Society, The Ohio State University, 2003
• Presidential Fellowship Nomination, The Ohio State University, 2002

Professional Societies

• The American Association for the Advancement of Science
• International Society of Molecular Plant-Microbe Interactions
• American Society of Plant Biologists

Degrees

• 2003 PhD The Ohio State University
• 1998 BS

Publications

Li W., K. Yadeta, J.M. Elmore, G. Coaker. (2013) The Pseudomonas effector HopQ1 promotes bacterial virulence and interacts with tomato 14-3-3 proteins in a phosphorylation dependent manner. Plant Physiology. 161(4):2062-74. *Selected as an ‘Editor’s Choice’

Li W., Y.H. Chiang, G. Coaker. (2013). The HopQ1 effector’s nucleoside hydrolase-like domain is required for bacterial virulence in Arabidopsis and tomato, but not host recognition in tobacco. PLoS ONE 8(3): e59684. doi:10.1371/journal.pone.0059684

Henry L., K. Yadeta, G. Coaker. (2013) Recognition of bacterial plant pathogens: local, systemic and transgenerational immunity. New Phytologist. Online early doi: 10.1111/nph.12214

Cui F., S.Wu, W. Sun, G. Coaker, B. Kunkel, P. He, and L. Shan. (2013). Pseudomonas syringae type III effector AvrRpt2 promotes pathogen virulence via stimulating Arabidopsis Aux/IAA protein turnover. Plant Physiology. 162:1018-29.

Park S.W., W. Li, S. Kim, J.D. Kittle, M.M.R. Ambavaram, S. Luan, A.R. Esker, D. Tholl, M. Ellerstrőm, G. Coaker, T.K. Mitchell, A. Pereira, K.J. Dietz, C.B. Lawrence. (2013) Cyclophilin 20-3 Relays a 12-Oxo-Phytodienoic Acid Signal During Stress Responsive Regulation of Cellular Redox Homeostasis. PNAS 110:9559-64. *Highlighted by PNAS commentary

Elmore JM, Liu J, Smith B, Phinney B, Coaker G. 2012. Quantitative proteomics reveals dynamic changes in the plasma membrane proteome during Arabidopsis immune signaling. Mol Cell Proteomics. 11(4):M111.014555.

Rastogi G, Sbodio A, Tech JJ, Suslow TV, Coaker GL*, Leveau JH*. 2012. Leaf microbiota in an agroecosystem: spatiotemporal variation in bacterial community composition on field-grown lettuce. ISME J. [Epub ahead of print] doi: 10.1038/ismej.2012.32 * co-corresponding authors

Liu J., J.M. Elmore, Z.J. Lin, and G. Coaker. 2011. A Receptor-like Cytoplasmic Kinase Phosphorylates the Host Target RIN4, Leading to the Activation of a Plant Innate Immune Receptor. Cell Host & Microbe. 9:137-46.

Elmore J.M. and G. Coaker. 2011. Biochemical Purification of Protein Complexes. Methods in Molecular Biology: Plant Immunity 712:31-44.

Elmore JM, Z.J. Lin ZJ, and G. Coaker. 2011. Plant NB-LRR signaling: upstreams and downstreams. Current Opinion in Plant Biol. 14(4):365-71.

Wilton M., R. Subramaniam, J.M. Elmore, C. Felsenteir, G. Coaker, and D. Desveaux. 2010. The Type III Effector HopF2Pto Targets Arabidopsis RIN4 Protein to promote Pseudomonas syringae virulence. PNAS 107: 2349-2354.

Cai R., J. Lewis, S. Yan, H. Liu, C.R. Clarke, F. Campanile, N.F. Almeida, D.J. Studholme, M. Lindeberg, D. Schneider, M. Zaccardelli, J.C. Setubal, N.P. Morales-Lizcano, A. Bernal, G. Coaker, C. Baker, C.L. Bender, S. Leman, and B.A. Vinatzer. 2011. The plant pathogen Pseudomonas syringe pv. tomato is genetically monomorphic and under strong selection to evade tomato immunity. PLoS Pathogens 7(8):e1002130.

Lui J., J.M. Elmore, A.J. Fuglsang, M.G. Palmgren, B. Staskawicz, and G. Coaker. 2009. RIN4 functions with plasma membrane H+-ATPases to regulate stomatal apertures during pathogen attack. PLoS Biology 7(6): e1000139.