Jason P. Eiserich

Position Title
Associate Professor

Unit
Department of Internal Medicine (Nephrology), School of Medicine
Department of Physiology and Membrane Biology, School of Medicine

Genome and Biomedical Sciences Facility, Rm. 6313
Bio

Profile Introduction

Oxidative signaling, inflammation, and mechanisms underlying acute and chronic vascular dysfunction

Research Interests

Oxidative signaling, inflammation, and mechanisms underlying acute and chronic vascular dysfunction

Grad Group Affiliations

  • Pharmacology and Toxicology Graduate Group

Specialties / Focus

  • Cardiorespiratory Physiology
  • Cellular Physiology
  • Molecular Physiology

Degrees

  • 1992 BS Environmental Toxicology University of California, Davis
  • 1997 PhD Environmental Chemistry University of California, Davis

Publications

Eiserich JP, Baldus S, Brennan ML, Ma W, Zhang C, Tousson A, Castro L, Lusis AJ, Nauseef WM, White CR and Freeman BA. 2002. Myeloperoxidase, a leukocyte-derived vascular NO oxidase. Science. 296:2391-2394

Eiserich JP, Estévez AG, Bamberg TV, Ye YZ, Chumley PH, Beckman JS and Freeman BA. 1999. Microtubule dysfunction by posttranslational nitrotyrosination of a-tubulin: A nitric oxide-dependent mechanism of cellular injury. Proc. Natl. Acad. Sci. USA. 96:636

Eiserich JP, Hristova M, Cross CE, Jones AD, Freeman BA, Halliwell B and van der Vliet A. 1998. Formation of nitric oxide-derived inflammatory oxidants by myeloperoxidase in neutrophils. Nature. 391:393-397

Tags