Department of Animal Science, College of Agricultural and Environmental Sciences
Mammary gland developmental biology, lactation, and breast cancer
Our lab seeks to define the processes underlying how the mammary glands - either during their growth, for milk synthesis, or in the case of breast cancer - respond to hormonal signals. We use a variety of methods, animal models and systems to study this regulation ranging from the molecular to the whole organism. In particular we are interested in how hormones such as estrogen, progesterone and prolactin affect tissue function and how factors such as diet and lifestyle also can have positive or negative effects.
Grad Group Affiliations
- Animal Biology
- Integrative Genetics and Genomics
Specialties / Focus
- Animal Genomics
- Human Genetics and Genomics
- Integrated Genetics and Genomics
- ANS 124 Lactation, Winter
- Hovey Lab http://animalscience.ucdavis.edu/hoveylab/
Honors and Awards
- 2012 - H. Allen Tucker award for mentoring - American Soc. Animal Sci.
- 2015 - UCDavis Academic Senate Teaching Prize
- 1992 BS Agricultural Science (Hons) University of Queensland, Australia
- 1997 PhD Animal Science Massey University, New Zealand
Berryhill, G.E., Gloviczki, J.M., Trott, J.F., Aimo, L., Kraft, J., Cardiff, R.D., Paul, C.T., Petrie, W.K., Lock, A.L., Hovey, R.C. (2012) Diet-induced metabolic change induces estrogen-independent allometric mammary growth. Proceedings of the National Academy of Sciences. 109(40):16294–16299.
Rowson-Hodel, A.R., Manjarin, R., Trott, J.F., Cardiff, R.D., Borowsky, A.D., and Hovey, R.C. (2015) Neoplastic transformation of porcine mammary epithelial cells in vitro and tumor formation in vivo. BMC Cancer. In press.
Schennink, A., Trott, J.F., Berryhill, G.E., Donovan, C.E., Manjarin, R., VanKlompenberg, M.K., Rowson-Hodel, A.R., Luis, M.O., and Hovey, R.C. (2015) Alcohol intake stimulates epithelial proliferation in an authentic model of the human breast. Reproductive Toxicology, 54:93-100.
Schennink, A., Trott, J.F., Manjarin, R, Lemay, D.G., Freking, B.A., and Hovey, R.C. (2015) Comparative genomics reveals tissue-specific regulation of prolactin receptor gene expression. Journal of Molecular Endocrinology, 54(1): 1-15.