Sheila David

Sheila David

Position Title

Department of Chemistry

Chemistry Annex, Rm. 2471 Davis, CA 95616

Profile Introduction

Chemical Biology of Base Excision Repair

Grad Group Affiliations

  • Biochemistry, Molecular, Cellular and Developmental Biology
  • Chemistry


  • Che 8A Elementary Organic Chemistry, Fall
  • MCB 221A Physical Biochemistry, Fall
  • Che 135 Advanced Bioorganic Chemistry Laboratory, Spring
  • Che 221D Special Topics: Chemical Biology of Nucleic Acids


  • 370 Chemistry
    • Cindy Khuu, Liz Lotsof, Merve Demir, Robert Van Ostrand, Kori Lay, Chandrima Majumdar, Alan Raetz, Doug Banda, Brittany Anderson-Steele

Honors and Awards

  • Beckman Young Investigator
  • AP Sloan Foundation
  • AAAS Fellow
  • American Chemical Society Fellow
  • ADVANCE Scholar Award

    Professional Societies

    • American Chemical Society
    • Environmental Mutagen Society


    • 1984 BA Chemistry Saint Olaf College
    • 1989 PhD Chemistry University of Minnesota


    "Unusual Structural Features of Hydantoin Lesions Translates into Efficient Recognition by Escherichia coli Fpg," Krishnamurthy, N., Muller, J.G., Burrows, C. J., David, S.S., Biochemistry, 2007, 46, 9355-9365.

    "Base-excision repair of oxidative DNA damage, " David, S. S., O'Shea, V.L., Kundu, S., Nature, 2007, 447, 941-950.

    "An Electron Trap for DNA-bound Repair Enzymes: A Strategy for DNA-mediated Signaling," Yavin, E., Stemp, E.D.A., O'Shea, V.L., David, S. S., Barton, J.K., Proc. Natl. Acad. Sci, USA, 2006, 103, 3610-3614.

    "Insight into the Role of Tyrosine 82 and Glycine 253 in the Escherichia coli Adenine Glycosylase MutY, " Livingston, A.L., Kundu, S., Pozzi, M.H., Anderson, D.W., David, S. S., Biochemistry, 2005, 44, 14179-14190.

    "A Role for Iron-Sulfur Clusters in DNA Repair, Lukianova, O.A., David, S. S., Curr. Op. Chem. Biol., 2005, 9, 145-151.