C. K. James Shen

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Position Title
Professor Emeritus

  • Molecular and Cellular Biology
Bio

Research Interests

In my work as a geneticist, I have concentrated on the study of chromatin structure and gene regulation. My research has explored how the organization of chromatin influences gene expression and cellular differentiation. By understanding the molecular mechanisms that control chromatin dynamics, I aim to uncover new insights into gene regulation and its implications for development and disease. My work is driven by a passion for advancing genetic research and improving our understanding of cellular processes.

Education and Degree(s)
  • 1971 B.S. in Chemistry, National Taiwan University
  • 1977 Ph.D. in Chemistry, University of California, Berkeley
Publications
  • Gavva NR, R Gavva, K Ermekova, M Sudol, and C-KJ Shen. 1997. Interaction of WW domains with hematopoietic transcription factor p45/NF-E2 and RNA polymerase II. Journal of Biological Chemistry. 272(39):24105-24108
  • Bailey AD, CC Shen, and C-KJ Shen. 1997. Molecular origin of the mosaic sequence of higher primate alpha-globin duplication units. Proceedings of the National Academy of Sciences. 94:5177-5182
  • Rombel I, KY Hu, Q Zhang, T Papayannopoulou, G Stamatoyannopoulos, and C-KJ Shen. 1995. Transcriptional activation of human adult alpha-globin genes by hypersensitive site-40 enhancer: function of nuclear factor-binding motifs occupied in erythroid cells.

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