Ernest S. Chang

Ernest Chang

Professor Emeritus

  • Neurobiology, Physiology and Behavior

Research Interests

My laboratory is broadly concerned with the mechanisms of development and the physiological ecology of marine and other invertebrates, especially those mechanisms involving hormonal and pheromonal cues. More specifically, we are conducting projects on:

  1. the molecular cloning of peptide hormones from the eyestalk of crustaceans (principally the lobster) that control molting
  2. the characterization of insulin-like growth factors from crustaceans
  3. pheromones and neurotransmitters that influence reproductive and aggressive behavior in crustaceans
  4. endocrine control of female reproduction in lobsters and marine
    shrimp
  5. the actions of ecdysteroids and methyl farnesoate in crustaceans via their hormone receptors
  6. characterization of muscle proteins in crustacean limbs during the molt cycle and development
  7. the physiological ecology of development and metamorphosis of marine invertebrates
  8. stress responses (hormones and heat-shock proteins) in crustaceans
Education and Degree(s)
  • 1973 B.A. in Zoology, University of California, Berkeley
  • 1978 Ph.D. in Biology, University of California, Los Angeles
Publications
  • Covi, J. A., Bader, B. D., Chang, E. S., and Mykles, D. L. 2010. Molt cycle regulation of protein synthesis in skeletal muscle of the blackback land crab, Gecarcinus lateralis, and the differential expression of a myostatin-like factor during atrophy induced by molting or unweighting. J. Exp. Biol. 213:172-183.
  • Lund, H. S., Wang, T., Chang, E. S., Pedersen, L. F., Taylor, E. W., Pedersen, P. B., and McKenzie, D. J. 2009. Recovery by the Norway lobster Nephrops norvegicus (L.) from the physiological stresses of trawling: influence of season and live-storage position. J. Exp. Mar. Biol. Ecol. 373:124-132.
  • Zarubin, T. P., Chang, E. S., and Mykles, D. L. 2009. Expression of recombinant eyestalk crustacean hyperglycemic hormone from the tropical land crab, Gecarcinus lateralis: Effects on hemolymph glucose and Y-organ ecdysteroidogenesis. Molec. Biol. Rep. 36:1231-1237.
  • Covi, J. A., Chang, E. S., and Mykles, D. L. 2009. Conserved role of cyclic nucleotides in the regulation of ecdysteroidogenesis by the crustacean molting gland. Comp. Biochem. Physiol. A 152:470-477.
  • Covi, J., Gomez, A., Chang, S., Lee, K., Chang, E., and Mykles, D. 2008. Repression of Y-organ ecdysteroidogenesis by cyclic nucleotides and agonists of NO-sensitive guanylyl cyclase. In: “4th Meeting of Comparative Biochemists and Physiologists in Africa - Mara 2008: Molecules to Migration: The Pressures of Life” (S. Morris, and A. Vosloo, eds.), pp. 3

Tags

Academic Departments Department of Neurobiology, Physiology and Behavior