C. K. James Shen

Position Title
Professor Emeritus

Department of Molecular and Cellular Biology, College of Biological Sciences

204A Briggs Hall

Research Interests

Gene regulation and chromosome structure in human cells. Molecular mechanisms of transcriptional regulation of human alpha- and beta-globin gene families.


  • 1971 BS Chemistry National Taiwan University
  • 1977 PhD Chemistry University of California, Berkeley


Gavva NR, R Gavva, K Ermekova, M Sudol, and C-KJ Shen. 1997. Interaction of WW domains with hematopoietic transcription factor p45/NF-E2 and RNA polymerase II. Journal of Biological Chemistry. 272(39):24105-24108

Bailey AD, CC Shen, and C-KJ Shen. 1997. Molecular origin of the mosaic sequence of higher primate alpha-globin duplication units. Proceedings of the National Academy of Sciences. 94:5177-5182

Rombel I, KY Hu, Q Zhang, T Papayannopoulou, G Stamatoyannopoulos, and C-KJ Shen. 1995. Transcriptional activation of human adult alpha-globin genes by hypersensitive site-40 enhancer: function of nuclear factor-binding motifs occupied in erythroid cells.