Ian F. Korf

Ian Korf

Position Title

  • Molecular and Cellular Biology
4333 Genome and Biomedical Sciences Facility

Research Interests

High-throughput technologies are transforming biology, medicine, agriculture, and related fields. Biology is now incredibly data-rich and requires computers to organize and analyze the data. My research program mixes -omic technologies and information technology to make new discoveries in genome structure and function. My lab is highly collaborative, and we always welcome potential research partners. My students can all do lab work and program, and many are co-mentored. Current interests include milk biology, gene prediction, genome assembly, sequence alignment, DNA-protein interactions, intron function, epigenetics, and more.

Education and Degree(s)
  • 1989 B.A. in Genetics, Cornell University
  • 1996 Ph.D. in Molecular, Cellular, and Developmental Biology, Indiana University Bloomington
  • Laufer BI, Hwang H, Jianu JM, Mordaunt CE, Korf IF, Hertz-Picciotto I, LaSalle JM. Low-pass whole genome bisulfite sequencing of neonatal dried blood spots identifies a role for RUNX1 in Down syndrome DNA methylation profiles. Hum Mol Genet. 2021 Jan 6;29(21):3465-3476. doi: 10.1093/hmg/ddaa218. PubMed PMID: 33001180; PubMed Central PMCID: PMC7788293.
  • Halstead MM, Kern C, Saelao P, Wang Y, Chanthavixay G, Medrano JF, Van Eenennaam AL, Korf I, Tuggle CK, Ernst CW, Zhou H, Ross PJ. A comparative analysis of chromatin accessibility in cattle, pig, and mouse tissues. BMC Genomics. 2020 Oct 7;21(1):698. doi: 10.1186/s12864-020-07078-9. PubMed PMID: 33028202; PubMed Central PMCID: PMC7541309.
  • Westreich ST, Salcedo J, Durbin-Johnson B, Smilowitz JT, Korf I, Mills DA, Barile D, Lemay DG. Fecal metatranscriptomics and glycomics suggest that bovine milk oligosaccharides are fully utilized by healthy adults. J Nutr Biochem. 2020 May;79:108340. doi: 10.1016/j.jnutbio.2020.108340. Epub 2020 Jan 17. PubMed PMID: 32028108; PubMed Central PMCID: PMC72
  • Treiber ML, Taft DH, Korf I, Mills DA, Lemay DG. Pre- and post-sequencing recommendations for functional annotation of human fecal metagenomes. BMC Bioinformatics. 2020 Feb 24;21(1):74. doi: 10.1186/s12859-020-3416-y. PubMed PMID: 32093654; PubMed Central PMCID: PMC7041091.
  • Chin EL, Huang L, Bouzid YY, Kirschke CP, Durbin-Johnson B, Baldiviez LM, Bonnel EL, Keim NL, Korf I, Stephensen CB, Lemay DG. Association of Lactase Persistence Genotypes (rs4988235) and Ethnicity with Dairy Intake in a Healthy U.S. Population. Nutrients. 2019 Aug 10;11(8). doi: 10.3390/nu11081860. PubMed PMID: 31405126; PubMed Central PMCID: PMC672395