Irwin H. Segel

Irwin Segel headshot

Professor Emeritus

  • Molecular and Cellular Biology

Research Interests

Enzymology, physiology, and regulation of sulfur metabolism with emphasis on the enzymes of inorganic sulfate activation in fungi, plants, animals, and bacteria. Enzymes of thermophilic fungi.

Education and Degree(s)
  • 1957 B.S. in Chemistry, Rensselaer Polytechnic Institute, New York
  • 1960 M.S. in Biochemistry, University of Wisconsin
  • 1962 Ph.D. in Biochemistry, University of Wisconsin
Publications
  • MacRae I. J., Segel, I. H., and Fisher, A. J.. 2000. Crystal Structure of APS Kinase from Penicillium chrysogenum.. Biochemistry. 39:1613 - 1621
  • MacRae, I. J., Hanna, E., Ho, J. D., Fisher, A. J., and Segel, I. H. . 2000. Induction of positive cooperativity by amino acid replacements within the C-terminal domain of P. chrysogenum ATP sulfurylase.. Journal of Biological Chemistry. 275:36303-36310
  • MacRae, I., A. B. Rose, and Segel, I. H.. 1998. Adenosine 5'-Phosphosulfate (APS) Kinase from Penicllium chrysogenum: Site Directed Mutagenesis Studies on Putative Phosphoryl-Accepting and ATP P - Loop residues. . Journal of Biological Chemistry. 273:

Tags

Academic Departments Department of Molecular and Cellular Biology