Position Title
Professor Emeritus
Unit
Department of Molecular and Cellular Biology, College of Biological Sciences
Research Interests
Enzymology, physiology, and regulation of sulfur metabolism with emphasis on the enzymes of inorganic sulfate activation in fungi, plants, animals, and bacteria. Enzymes of thermophilic fungi
Grad Group Affiliations
- Microbiology
Degrees
- 1957 BS Chemistry Rensselaer Polytechnic Institute, New York
- 1960 MS Biochemistry University of Wisconsin
- 1962 PhD Biochemistry University of Wisconsin
Publications
MacRae I. J., Segel, I. H., and Fisher, A. J.. 2000. Crystal Structure of APS Kinase from Penicillium chrysogenum.. Biochemistry. 39:1613 - 1621
MacRae, I. J., Hanna, E., Ho, J. D., Fisher, A. J., and Segel, I. H. . 2000. Induction of positive cooperativity by amino acid replacements within the C-terminal domain of P. chrysogenum ATP sulfurylase.. Journal of Biological Chemistry. 275:36303-36310
MacRae, I., A. B. Rose, and Segel, I. H.. 1998. Adenosine 5'-Phosphosulfate (APS) Kinase from Penicllium chrysogenum: Site Directed Mutagenesis Studies on Putative Phosphoryl-Accepting and ATP P - Loop residues. . Journal of Biological Chemistry. 273:
