Lucas R. Smith


Position Title
Assistant Professor

Department of Neurobiology, Physiology and Behavior, College of Biological Sciences
Department of Physical Medicine and Rehabilitation, School of Medicine

189 Briggs Hall

Research Interests

Extracellular matrix in skeletal muscle physiology

Our research is focused on understanding the mechanisms by which skeletal muscle adapts, with an emphasis on the fibrotic process that is associated with many muscle pathologies including muscular dystrophies.  We seek to uncover the relationship between the structure of the extracellular matrix and both the mechanical function of muscle and the regenerative capacity of muscle stem cells. These studies will guide novel therapies for fibrotic muscle diseases.

Grad Group Affiliations

  • Biochemistry, Molecular, Cellular and Developmental Biology
  • Biomedical Engineering
  • Molecular, Cellular and Integrative Physiology

Specialties / Focus

  • Cell Biology
  • Cell Division and the Cytoskeleton
  • Cellular Physiology
  • Cellular Responses to Toxins and Stress
  • Differentiation, Morphogenesis and Wound Healing
  • DNA Repair
  • Exercise Physiology
  • Molecular Medicine
  • Molecular Physiology
  • RNA
  • Stem Cell Biology


  • TBD

Honors and Awards

  • K99 Receipient, NIH National Institute of Arthritis, Skin, and Musculoskeletal Diseases (2016)
  • Gayle G. Arnold Award, American Academy of Cerebral Palsy and Disability Medicine, (2013)
  • Siebel Scholar Award, Siebel Foundation (2010)

    Professional Societies

    • Biomedical Engineering Society
    • American Physiological Society
    • American Society for Cell Biology


    • Ph.D. Department of Bioengineering, University of California, San Diego
    • B.S. Department of Bioengineering, University of Washington


    Google Scholar Citations