Mark McNamee

Mark McNamee

Position Title
Professor Emeritus

1141 Life Sciences Addition
Bio

Research Interests

Structure and function of nerve membrane proteins, particularly the nicotinic acetylcholine receptor (nAChR). Effects of membrane lipids on nAChR conformation, ligand binding, and ion permeati

Degrees

  • 1968 BS Chemistry Massachusetts Institute of Technology
  • 1973 PhD Physical Chemistry Stanford University

Publications

Lasalde JA, S Tamamizu, Y-H Lee, and MG McNamee. 1999. Alteration in ion channel function of mouse nicotinic acetylcholine receptor by mutations in the M4 transmembrane domain. Journal of Membrane Biology. 170:157-164

Kim J and MG McNamee. 1998. Topological disposition of Cys222 inthe a subunit of nicotinic acetylcholine receptor analyzed by fluorescence- quenching and electron paramagnetic resonance measurements. Biochemistry. 37:4680-4686

Tamamizu S, MG McNamee, G Guzman, J Santiago, LV Rojas, and JA Lasalde. 1999. Functional effects of periodic tryptophan substitutions in the alpha M4 transmembrane domain of the Torpedo californica nicotinic acetylcholine receptor. Biochemistry. :(