Department of Molecular and Cellular Biology
Mechanisms and regulation of transcription in eukaryotic cells with a special emphasis on the role of phosphorylation in the regulation of RNA polymerase II activity.
Grad Group Affiliations
- Integrative Genetics and Genomics
- MCB 121 Molecular Biology of Eukaryotic Cells, Winter
Honors and Awards
- AAAS Fellow
- American Society for Biochemistry and Molecular Biology
- 1963 BS Botany Iowa State University
- 1968 PhD Biochemistry California Institute of Technology
Lehman, A. L. and Dahmus, M. E. The sensitivity of RNA polymerase II in elongation complexes to C-terminal domain phosphatase. Journal of Biological Chemistry, 275, 14923-14932 (2000).
Marshall, N. F. and Dahmus, M. E. C-terminal domain phosphatase sensitivity of RNA polymerase II in early elongation complexes on the HIV-1 and adenovirus 2 major late templates. Journal of Biological Chemistry, 275, 32430-32437 (2000).
Lin, P., Marshall, N. F. and Dahmus, M.E. CTD phosphatase, role in RNA polymerase II cycling and the regulation of transcript elongation. in Progress in Nucleic Acids Research and Molecular Biology, ed. K. Moldave, Academic Press, 72, 333-365 (2002).
Lin, P. S., Dubois, M.F. and Dahmus, M. E. FCP1 dephosphorylates phosphoserine 2 and 5 within the carboxyl-terminal domain of RNA polymerase II. Journal of Biological Chemistry, 277, 45949-45956 (2002).
Yeo, M., Lin. P. S., Dahmus, M. E. and Gill, G. N. RNA polymerase II C-terminal domain phosphatases specific for serine 5 in the heptade repeat regulate transcription. Journal of Biological Chemistry, 278, 26078-26085 (2003).