Position Title
Professor Emeritus
Position Title
Professor Emeritus
- Molecular and Cellular Biology
Bio
Research Interests
Role of cell-cell and cell-extracellular matrix adhesion in the determination of tissue structure. Cell adhesion to the extracellular matrix: regulation of cell motility and proliferation. Mechanisms of intercellular invasion. Regulation of embryonic morphogenesis. Mode of action of peptide growth factors. Comparative biology of evolutionarily conserved effectors of the innate immune system: a2-macroglobulin & C-reactive protein. Role of the blood clotting system in immunity. Lipopolysaccharide/endotoxin: immune defense against endotoxemia, phylogenetic distribution of lipopolysaccharide.
Education and Degree(s)
- 1961 B.S. in Chemistry, University of Rochester
- 1966 Ph.D. in Biology, Johns Hopkins University
Publications
- Armstrong, P.B . 2015. Comparative biology of the pentraxin protein family, an evolutionarily conserved component of the innate immune system. Int. Rev. Cell Mol. Biol. 316:1-47.
- Chaikeeratisak, V., Tassanakajon, A., Armstrong, P.B. 2014 Interaction of pathogenic Vibrio bacteria with the blood clot of the pacific white shrimp, Litopenaeus vannamei. Biol. Bull. 226:102-110.
- Armstrong, M.T., Rickles, F., Armstrong, P.B. 2013. Capture of lipopolysaccharide (endotoxin) by the blood clot: a comparative study. PLOS ONE 8:e80192 available online at http://dx.plos.org/10.1371/journal.pone.0080192.
- Shrive, A.K., Burns, I., Chou, H.-T., Stahlberg, H., Armstrong, P.B., and Greenhough, T.J. 2009. Crystal structures of Limulus SAP-like pentraxin reveal two molecular aggregations. J. Mol. Biol. 386:1240-1254
- Harrington, J.M., Chou, H.-T., Gutsmann, T., Gelhaus, C., Stahlberg, H., Leippe, M., and Armstrong, P.B. 2009. Membrane activity of a C-reactive protein. FEBS Lett. 583:1001-1005.