In a study appearing in PLOS Genetics, Professor Sean Burgess and her colleagues highlight how mutations in a gene called spo11 can lead to zebrafish males that are infertile and females that produce offspring with developmental problems.
When he enrolled at UC Davis, student Mackenzie Noon gravitated towards genetics. Today, he's an undergraduate researcher studying cancer at the chromosomal level in the lab of Professor Ken Kaplan, Department of Molecular and Cellular Biology.
Microtubule fibers are hollow rods made of much smaller tubulin subunits that spontaneously assemble at one end of the rod, but exactly how they do this inside the crowded environment of living cells has been a mystery. UC Davis researchers have uncovered the mechanism that puts these blocks in place, illustrated in a new animation.
During oocyte quality control, a decision is made whether each oocyte should continue and join the reserve of eggs or undergo cellular death. New research from Neil Hunter’s laboratory at UC Davis reveals the surprising way that this critical oocyte quality control process works.
With a grant from the National Science Foundation, Assistant Professor Celina Juliano will help develop genomic tools that will promote regenerative research and hopefully increase the number of researchers using Hydra as a model system.
After a long day of teaching and research, biochemists Richard McKenney and Kassandra Ori-McKenney usually find themselves on their patio discussing topics like the cytoskeleton and motor proteins. It’s shop talk for the couple, both assistant professors in the Department of Molecular and Cellular Biology.
It’s been widely reported that investigators got a break in the East Area Rapist/Golden State Killer case when they uploaded a DNA profile to a genealogy database, GEDmatch, and identified relatives of the suspect, Joseph DeAngelo. Did they get lucky, or did they have a good chance of finding him? UC Davis population biologists Graham Coop and M. D. “Doc” Edge have written a nice explainer of the science behind this search.
Mark Winey, dean of the College of Biological Sciences at UC Davis, became fascinated by science at an early age. But the draw to biology—specifically, genetics—was prompted by Winey’s younger sister Christine, who as an infant was diagnosed with an inherited metabolic disease called galactosemia.
In a study appearing in Current Biology, Michael Turelli, distinguished professor of genetics in the Department of Evolution and Ecology, and his colleagues traced the spread of closely related Wolbachia across Drosophila fly species. They found that while the flies evolutionarily diverged tens of millions of years ago, their Wolbachia bacteria diverged only tens of thousands of years ago.
Software inspired by speech recognition technology could help scientists understand the secret language inside cells. A machine learning algorithm called patteRNA, designed by UC Davis researchers, rapidly mines ribonucleic acid, commonly called RNA, for specific structures, providing a new method to establish links between structure, function and disease.
For many, breast cancer is more than just a disease – it’s personal. One in eight women will be diagnosed with breast cancer at some point in their lives. But through new discoveries at the genetic level, the personal nature of cancer will eventually be what helps to beat it.