Event Date
Simon Powell, Department Chair, Professor and Member, Memorial Sloan Kettering Cancer Center, presents "The Role of Human RAD52 in Genome Protection for Homologous Recombination Deficiency".
Professor Simon Powell has worked in cancer research and treatment for over 30 years. In laboratory research, his major focus is tumor-specific defects in DNA repair. In recent years, he has continued to focus on the pathway of homologous recombination and studying the role of the breast cancer susceptibility genes, BRCA1 and BRCA2. As a result, this led to researching the differences between double-strand break responses and blocked replication fork. The major goal is how to optimize synthetic lethal strategies for targeting homologous recombination defective tumors. In this regard, their discovery of the role of human RAD52 in BRCA-deficient cells aligns well with their past and future research plans.
Host: Sara Hariri (sahariri@ucdavis.edu)