Event Date
Gheorghe Chistol, Assistant Professor in Chemical and Systems Biology, Stanford School of Medicine, presents "Single-Molecule Imaging Reveals the Mechanism of Bidirectional Replication Initiation".
Gheorghe was born in Moldova (Eastern Europe) in 1984, and was initially interested in physics, astronomy and extra-solar planets. Gheorghe did his undergraduate at MIT (class of 2007) in physics, dabbled in nuclear physics, astrophysics (gravitational lenses). In graduate school at Berkeley, Gheorghe became interested in biophysics, and worked in the group of Carlos Bustamante measuring how tiny molecular motors translocate DNA. Having realized how little biochemistry he knew, Gheorghe did a postdoc the lab of Johannes Walter at Harvard Medical School where he spent 3 yrs learning to clone and purify proteins. There Gheorghe developed a single-molecule method that his lab has since streamlined and made routine. In 2019 Gheorghe started his lab at Stanford in the dept of Chemical and Systems biology. The Chistol lab uses biochemistry and single-molecule imaging to "illuminate" molecular mechanisms of genome maintenance.
Host: Wolf Heyer (wdheyer@ucdavis.edu)