Carolynn Patten

Carolynn-Patten headshot

Position Title
Professor

  • Neurobiology, Physiology and Behavior
  • Physical Medicine and Rehabilitation
Bio

Research Interests

My research focuses on understanding the neural basis of human movement with overriding goals of elucidating mechanisms of movement dysfunction with aging and in adult neuropathologies; determining capacity for motor recovery following central nervous system injury; and identifying critical factors that contribute to rehabilitation efficacy. To achieve these goals, my research program investigates neural mechanisms and biomechanical consequences of CNS pathologies causing motor dysfunction; development of biomarkers of motor recovery; and novel means to induce neuroplasticity and recovery. This translational neuroscience research combines expertise in neurophysiological (i.e., transcranial magnetic stimulation (TMS), EEG, EMG, motor unit recordings, reflex probes), neuroimaging, biomechanical (measures of force production, kinetics), behavioral (kinematics), and clinical approaches to study human performance, and as a result, crosses disciplines of motor control, neuroscience, biomechanics, clinical medicine, rehabilitation, and bioengineering. My research supports clinical care in neurorehabilitation or individuals with motor dysfunction resulting from neuropathologies, such as stroke, to aid in recovery, restore activity participation and optimize quality of life.

Education and Degree(s)
  • 1980, B.A., University of Washington
  • 1992, M.S.P.T., Boston University
  • 1998, Ph.D., University of Massachusetts, Amherst
  • 1998-2001, Postdoctoral Fellowship, Stanford University, VA Rehab Research Center
Publications
  • Ao D, Li G, Shourijeh MS*, Patten C, and Fregly BJ. EMG-driven musculoskeletal model calibration with wrapping surface personalization. IEEE Trans Neur Sys and Rehab Eng, accepted 08 Oct 2023
  • Banks CL*, Patten C†. Development of an Assessment of Bilateral Locomotor Efficacy for Individuals Poststroke, Gait & Posture, 2023: 172-177; https://doi.org/10.1016/j.gaitpost.2023.05.012. PMID: 37210850
  • Young BM, Holman EA, Cramer SC, STRONG Study Investigators. Rehabilitation Therapy Doses Are Low After Stroke and Predicted by Clinical Factors. Stroke. 2023 Feb; doi: 10.1161/STROKEAHA.122.041098. PMID:36734234
  • Srivastava S, Seamon BG, Patten C, Kautz SA. Relationship between parameters of body weight supported treadmill training and muscle activity patterns in post-stroke gait, Exp Br Res, 2023 Jan; 10.1007/s00221-023-06551-7, PMID: 36639543
  • Vega MM, Li G, Shourijeh MS, Ao D, Weinschenk RC, Patten C, Font-Llagunes JM, Lewis VO, Fregly BJ. Computational Evaluation of Psoas Muscle Influence on Walking Function Following Internal Hemipelvectomy with Reconstruction, Fron Bioeng Biotech, Biomechanics, 2022 Sep 28;10:855870. doi:10.3389/fbioe.2022.855870. PMID: 36246391. PMCID: PMC9559731

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