Mitchell H. Singer

Mitchell Singer

Professor

  • Microbiology and Molecular Genetics
268 Briggs Hall

Research Interests

My lab primarily focuses on two aspects of development in the Gram negative social soil bacterium Myococcus xanthus:  1) identifying the hierarchical regulatory network that initiates and drives the developmental program and 2) determining the developmental link between DNA replication and the developmental program.  In both instances we rely on the transcriptional analysis to monitor progression through development.  My lab is also interested in the evolution of bacterial development in these ubiquitous bacteria and identifying core genes in the developmental process.

Graduate Program Affiliations

Education and Degree(s)
  • 1982 B.S. in Microbiology, University of Illinois
  • 1990 Ph.D. in Bacteriology, University of Wisconsin, Madison
Publications
  • Suen, G., J.S. Jakobsen, B.S. Goldman, M. Singer, A. G. Garza, and R.D. Welch. Bacterial Postgenomics: the Promise and Peril of Systems Biology. 2006 J. Bacteriol. 188:7999-8004
  • Pham, V.D., C.W. Shebelut, I.R. Jose, D.A. Hodgson, D.E. Whitworth and M. Singer. PhoP4 is Required for Proper Sporulation and Development-Specific Phosphatase Activities in Myxococcus xanthus. 2006. Microbiology. 152:1609-20
  • Viswanathan, P., M. Singer, and L. Kroos. Role of ?D in regulating genes and signals during Myxococcus xanthus development. 2006. J. Bacteriol. 188:3246-3256
  • Tzeng, L., T. N. Ellis, and M. Singer. DNA replication during aggregation phase is essential for Myxococcus xanthus fruiting body development. 2006. J. Bactiol. 188:2774-79
  • Diodati, M. E. , F. Ossa, N. B. Caberoy, I. R. Jose, W. Hiraiwa, M.M. Igo, M. Singer*, and A.G. Garza*. Nla18, a key regulatory protein required for normal growth and development in Myxococcus xanthus. 2006. J. Bacteriol 188:1733-43.

Tags

Academic Departments Department of Microbiology and Molecular Genetics