Female infants are born with several million immature egg cells, or oocytes. Over the course of the reproductive years, a few hundred of them will develop into mature eggs for potential fertilization. Because of this extended maturation process, the oocytes of humans and other mammals are vulnerable to both developmental exposures and the aging process.
Chemical engineer and microbiologist Priya Shah is unraveling the essential aspects of arboviruses - viruses transmitted by mosquitoes, ticks, or other arthropods - aiming to thwart this major source of emerging diseases by identifying novel therapeutic targets.
For her innovative research, she has been awarded $40,000 from a UC Davis endowment set up by anonymous donors. The awards, given annually since 2016, are designated for non-tenured ladder-track faculty.
Plants photosynthesize to survive, and bacteria divide to reproduce, but to accomplish these necessary biological functions, the cells of these organisms employ protein trafficking. More specifically, these functionalities, among many others, rely on the twin-arginine translocation (Tat) pathway, which, when properly functioning, allows for the transportation of proteins across cellular membranes.
The college is very pleased to welcome the newest members of its broad and diverse faculty. With appointments in the Departments of Evolution and Ecology, Plant Biology and Microbiology and Molecular Genetics, the new faculty are poised to make an impact on their respective areas of expertise, and on the classroom and laboratory experience of our students across the college.
Anya Brown
Assistant Professor Department of Evolution and Ecology
The success of E. coli bacteria depends on their ability to multiply very rapidly by dividing into new cells. The bacteria can divide as quickly as they can make an entire new copy of their DNA while minimizing errors. New work from researchers at the University of California, Davis College of Biological Sciences answers a key question about how E. coli fixes damage to DNA in the middle of duplicating it.
The U.S. Department of Energy is funding a project at the UC Davis College of Biological Sciences to study the function of genes that regulate growth and wood formation in poplar trees. The three-year, $2.5 million project is led by Nitzan Shabek, assistant professor in the UC Davis Department of Plant Biology together with Andrew Groover at the USDA Pacific Southwest Research Station in Davis and Justin Walley, Iowa State University.
In Alzheimer’s disease and other neurodegenerative dementias, proteins that normally play a role in healthy brain tissue turn bad, clumping together to form insoluble plaques and tangles as neurons wither and die. Exactly how these proteins are connected to disease — and whether they can be targeted in some way to slow, stop or reverse its progression — remains a challenging problem.
Fertility is finite for mammalian females. From birth, females possess a limited number of primordial follicles that are collectively called the ovarian reserve. Within each follicle is an oocyte that eventually becomes an egg. But with age, the viability of the ovarian reserve decreases.
“Despite its fundamental importance, our understanding how the ovarian reserve is established and maintained remains poor,” said UC Davis Professor Satoshi Namekawa, Department of Microbiology and Molecular Genetics.
Distinguished Professor Walter Leal of the Department of Molecular and Cellular Biology, and a former chair of the Department of Entomology, was inducted as a Fellow of the National Academy of Inventors (NAI) at a June ‘22 ceremony in Phoenix, Ariz.
This year’s graduate student awards emphasize the importance - and success - of mentoring younger scientists, and demonstrate the UC Davis commitment to collaboration, support and partnership that define interdisciplinary science. Graduate student awards support travel, research and professional development opportunities, and are made possible by generous philanthropic contributions to the college.
CBS Dean’s Mentorship Award
The Dean’s Mentorship Award recognizes graduate students who have demonstrated excellence in the mentorship of undergraduate students.
