Biochemistry, Molecular, Cellular and Developmental Biology Graduate Group

From Yeast to Zebrafish, New Insight on Birth Defects and Miscarriage

January 17, 2019
In a study appearing in PLOS Genetics, Professor Sean Burgess and her colleagues highlight how mutations in a gene called spo11 can lead to zebrafish males that are infertile and females that produce offspring with developmental problems.

Visualizing “Unfurling” Microtubule Growth

November 13, 2018
Microtubule fibers are hollow rods made of much smaller tubulin subunits that spontaneously assemble at one end of the rod, but exactly how they do this inside the crowded environment of living cells has been a mystery. UC Davis researchers have uncovered the mechanism that puts these blocks in place, illustrated in a new animation.

Wayward Ways: New Study Reveals How the Nucleus Travels

September 20, 2018
Using CRISPR/Cas9 gene editing tools, Dan Starr created mutant versions of the worm C. elegans, to explore how the nucleus moves and repositions itself in the eukaryotic cell.