A nerve cell resembles a vast tree with branches that communicate with thousands of other cells. To function, it depends on a motor protein that walks on two legs, hauling urgent cargo from the center of the cell to the faraway tips of every branch. Scientists have unveiled a new structure of this walking protein, showing how cells control it.
Cancer cells are quick to develop resistance to anti-tumor drugs. New research by scientists from the University of California, Davis shows how cancers adapt to evade a class of anti-tumor drugs called BET inhibitors and offers hope for more effective therapies.
As wildflowers go, the mountain jewelflower is demure, clever and quietly unbreakable. It has spread across many of California’s iconic landscapes, from Sonoma wine country to the oak-dotted foothills, even over the Sierra Crest, where snow covers the ground during winter.
The causes of male infertility can be hard to diagnose, with many tests failing to detect genetic defects. Sometimes, infertility doesn’t even involve the genes themselves. It can arise from improper folding of the father’s DNA in the sperm. If a couple conceives, this mispackaged DNA can damage the lifelong health of the child.
A kestrel swoops to grab a smaller bird on the wing and eats it, right in front of a group of men in the garden at California Health Care Facility, or CHCF, a prison in Stockton, where the garden has become both a thriving ecosystem and a science classroom for people incarcerated there. As the feathers fly, UC Davis researcher Laci Gerhart pulls out a bird guide and shows the incarcerated men how to identify the bird by its size and coloration, noting that kestrels are North America’s smallest raptor and one of the few that are sexually dimorphic.
Being a single mother of 20 is no joke, especially if the survival of a whole species depends on it.
A queen bumblebee faces this very challenge when she lays her first eggs in the spring: She is utterly alone, with no worker bees to help.
She flies miles each day, collecting nectar to feed her young. She builds a protective nursery from wax. When she’s not out foraging, she climbs atop her larvae and buzzes to warm them.
The genomics of peppermint are not as fresh as their flavor but scientists from the University of California, Davis, have found a way to breathe new genetic variation into the species.
Experiences in the first days and weeks of life can have a profound impact on humans — and birds. A new study led by Sage Madden, a graduate student working with Gail Patricelli, a professor of evolution and ecology, shows how weather conditions and family dynamics affect the growth of barn swallow (Hirundo rustica erythrogaster) chicks.
Thousands of times per year, a family’s moment of joy turns to unexpected grief. A seemingly healthy infant stops smiling or making eye contact. Their limbs grow weak. The tiny child suffers seizures and breathing problems.
Jawdat Al-Bassam, an associate professor of molecular and cellular biology at the University of California, Davis, often hears from these families. “I’ve gotten emails from folks all over the world,” he said.
Salicylic acid, the active molecule in aspirin and some acne medications, is a hormone in plants that is essential for immunity, but it’s a double-edged sword: too much can cause autoimmunity and stunt growth. In a new study published April 20 in Nature Communications,University of California, Davis, researchers discovered that plants use a surprising multi-layered system to regulate salicylic acid levels and keep their immune system in check.