Extramurally Funded Research

Muscular Dystrophy Mutations Leave Cells Short of "Packing Peanuts"

Emery-Dreifuss muscular dystrophy (EDMD) is a devastating genetic disease that causes progressive muscle weakness and wasting. EDMD is caused by mutations in proteins within the nuclear envelope, yet the disease disrupts the organization and function of entire muscle cells. A new study by UC Davis researchers reveals one mechanism that may explain this connection.

Secrets of Regeneration May Mimic Cancer

The tiny aquatic hydra looks fragile at first glance, with tentacles that are slender and translucent. But if you cut it in half, each fragment regenerates into a complete new animal. Scientists studying this amazing feat have discovered a surprising detail: to trigger healing, specialized cells first have to invade the wound in a manner similar to what cancer cells do as they spread through the body.

A DNA-Organizing Protein Offers New Insight into Infertility, IVF and Generational Health

The causes of male infertility can be hard to diagnose, with many tests failing to detect genetic defects. Sometimes, infertility doesn’t even involve the genes themselves. It can arise from improper folding of the father’s DNA in the sperm. If a couple conceives, this mispackaged DNA can damage the lifelong health of the child.

Training Naturalists Behind Prison Walls

A kestrel swoops to grab a smaller bird on the wing and eats it, right in front of a group of men in the garden at California Health Care Facility, or CHCF, a prison in Stockton, where the garden has become both a thriving ecosystem and a science classroom for people incarcerated there. As the feathers fly, UC Davis researcher Laci Gerhart pulls out a bird guide and shows the incarcerated men how to identify the bird by its size and coloration, noting that kestrels are North America’s smallest raptor and one of the few that are sexually dimorphic.