Plants need to be able to communicate with themselves—by sending signals from their leaves to their roots to their flowers—so that they can coordinate growth and optimize resource use. They also need to communicate with other plants and organisms, which they achieve by releasing volatile organic compounds (VOCs), tiny molecules that are often associated with distinct smells. Scientists know a lot about how plants emit these odorous signals, however very little is known about how they receive and interpret them.

For many, mathematics exists solely within the confines of a blackboard, a calculator or a textbook. But ask Javier Arsuaga and he’ll tell you that mathematics exists within us, right down to our DNA.

Researchers in the College of Biological Sciences have received a grant to study the role of the cerebellum in autism. “We need a more holistic understanding of the brain circuits that drive this disorder,” says Alex Nord, an associate professor of neurobiology, physiology and behavior (NPB), and a researcher at the Center for Neuroscience (CNS). “The cerebellum is a key component that has been largely overlooked until recently.”

Sorghum, or broomcorn, is a staple crop in sub-Saharan Africa, but approximately 20% of annual yields are lost due to infections with witchweed (Striga hermonthica), a parasitic plant that steals nutrients and water by latching onto the plant’s roots.

A chance observation in an undergraduate laboratory class has shed light on a key cleaning and recycling process carried out by all eukaryotic cells. Autophagy breaks down organelles, proteins and other molecules so their components can be reused and plays a protective role in preventing disease. However, when autophagy doesn’t work correctly, it’s associated with cancer and neurodegenerative diseases including Alzheimer’s. Previous research has uncovered how cells activate autophagy, but little is known about how it is switched off.

Our understanding of schizophrenia has increased greatly in recent years, as studies of large groups of people have identified a multitude of genetic variants that increase a person’s risk of the disease. But each of those individual risk factors accounts for “only a very minor amount of the overall risk,” said Alex Nord, a professor of neurobiology, physiology and behavior in the College of Biological Sciences and the Center for Neuroscience.

A promising new fungicide to fight devastating crop diseases has been identified by researchers at the University of California, Davis. The chemical, ebselen, prevented fungal infections in apples, grapes, strawberries, tomatoes and roses, and improved symptoms of pre-existing fungal infection in rice.

Early in the development of sperm, a strange event happens: the X and Y chromosomes condense into tight packages and are sequestered away from the other 44 human chromosomes. If any part of this process goes awry, the cells cannot mature into sperm. Researchers in the College of Biological Sciences have now identified an important link in this process — a little-known protein called ATF7IP2.

Ben Cox, a postdoctoral researcher in the lab of Celina Juliano, Department of Molecular and Cellular Biology, studies regeneration in Hydra vulgaris, a small cnidarian organism distantly related to the jellyfish. Cox is especially interested in tissue regeneration after injury and aims to determine how progenitor cells migrate and invade into injured tissues to restore lost cell populations, as well as how the extracellular matrix components are remodeled during this regeneration process.

Funding agencies and universities should make it more equitable for early-career investigators with non-traditional career paths to compete for grants and progress in their careers, argue four scholars with non-traditional backgrounds in a paper published in PLOS Biology in the fall of 2023.